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Anti-tumor activity of phenoxybenzamine and its inhibition of histone deacetylases
The principal finding from this study was the recognition that the α-adrenergic antagonist, phenoxybenzamine, possesses histone deacetylase inhibitory activity. Phenoxybenzamine is approved by the United States Food and Drug Administration for the treatment of hypertensive crises associated with tum...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999115/ https://www.ncbi.nlm.nih.gov/pubmed/29897996 http://dx.doi.org/10.1371/journal.pone.0198514 |