N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians

BACKGROUND AND OBJECTIVES: N-acetyltransferase 2 (NAT2) metabolize several drugs including isoniazid. We investigated the effect of genotype, geographical difference, and smoking habit on NAT2 phenotype in Ethiopians. METHODS: Genotyping for NAT2 191G > A, 341 T > C, 590G > A, and 857G >...

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Detalles Bibliográficos
Autores principales: Aklillu, Eleni, Carrillo, Juan Antonio, Makonnen, Eyasu, Bertilsson, Leif, Djordjevic, Natasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Pharmacogenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999125/
https://www.ncbi.nlm.nih.gov/pubmed/29589062
http://dx.doi.org/10.1007/s00228-018-2448-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999125/
https://www.ncbi.nlm.nih.gov/pubmed/29589062
http://dx.doi.org/10.1007/s00228-018-2448-y

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