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Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network
Biochemical pathways are often genetically encoded as simple transcription regulation networks, where one transcription factor regulates the expression of multiple genes in a pathway. The relative timing of each promoter’s activation and shut-off within the network can impact physiology. In the DNA...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999292/ https://www.ncbi.nlm.nih.gov/pubmed/29856734 http://dx.doi.org/10.1371/journal.pgen.1007405 |