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Delayed treatment of propofol inhibits lipopolysaccharide-induced inflammation in microglia through the PI3K/PKB pathway

Propofol is a short-acting intravenous anesthetic agent with potential neuroprotective effect. In this study, we aim to investigate whether delayed propofol treatment is protective against lipopolysaccharide (LPS)-stimulated inflammatory responses in microglial cells. Cultured BV2 microglial cells w...

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Detalles Bibliográficos
Autores principales: Luo, Jun, Huang, Baoyi, Zhang, Zhijing, Liu, Min, Luo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999385/
https://www.ncbi.nlm.nih.gov/pubmed/29742623
http://dx.doi.org/10.1097/WNR.0000000000001041