Cargando…

Delayed treatment of propofol inhibits lipopolysaccharide-induced inflammation in microglia through the PI3K/PKB pathway

Propofol is a short-acting intravenous anesthetic agent with potential neuroprotective effect. In this study, we aim to investigate whether delayed propofol treatment is protective against lipopolysaccharide (LPS)-stimulated inflammatory responses in microglial cells. Cultured BV2 microglial cells w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Jun, Huang, Baoyi, Zhang, Zhijing, Liu, Min, Luo, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Cellular, Molecular and Developmental Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999385/ https://www.ncbi.nlm.nih.gov/pubmed/29742623 http://dx.doi.org/10.1097/WNR.0000000000001041

Ejemplares similares

Nurr1 expression is modified by inflammation in microglia
por: Lallier, Scott W., et al.
Publicado: (2016)

Quercitrin improved cognitive impairment through inhibiting inflammation induced by microglia in Alzheimer’s disease mice
por: Wang, Lixin, et al.
Publicado: (2022)

Inhibition of inflammatory factor TNF-α by ferrostatin-1 in microglia regulates necroptosis of oligodendrocyte precursor cells
por: Chai, Zhi, et al.
Publicado: (2023)

Propofol Inhibits Microglial Activation via miR-106b/Pi3k/Akt Axis
por: Liu, Jianhui, et al.
Publicado: (2021)

Roxadustat (FG-4592) abated lipopolysaccharides-induced depressive-like symptoms via PI3K signaling
por: Li, Axiang, et al.
Publicado: (2023)

miR-128-3p inhibits the inflammation by targeting MAPK6 in penicillin-induced astrocytes
por: Pang, Yuejiu, et al.
Publicado: (2022)

Inhibition of immunoproteasome subunit low molecular mass polypeptide 7 with ONX-0914 improves hypoxic-ischemic brain damage via PI3K/Akt signaling
por: Zhou, Yue, et al.
Publicado: (2021)

Triggering of inflammasome by impaired autophagy in response to acute experimental Parkinson’s disease: involvement of the PI3K/Akt/mTOR pathway
por: Giacoppo, Sabrina, et al.
Publicado: (2017)

Recombinant human erythropoietin protects long-term cultured ageing primary nerve cells by upregulating the PI3K/Akt pathway
por: Wang, Huqing, et al.
Publicado: (2022)

Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients
por: Pérez-Tenorio, G, et al.
Publicado: (2002)

Molecular alterations in apoptotic pathways after PKB/Akt-mediated chemoresistance in NCI H460 cells
por: Hövelmann, S, et al.
Publicado: (2004)

Notoginsenoside R1 alleviates spinal cord injury by inhibiting oxidative stress, neuronal apoptosis, and inflammation via activating the nuclear factor erythroid 2 related factor 2/heme oxygenase-1 signaling pathway
por: Luo, Hongbo, et al.
Publicado: (2022)

Electroacupuncture relieves chronic pain by promoting microglia M2 polarization in lumbar disc herniation rats
por: Yang, Jia-Xuan, et al.
Publicado: (2023)

Tetrahydroxystilbene glycoside antagonizes β-amyloid-induced inflammatory injury in microglia cells by regulating PU.1 expression
por: Jiao, Chenli, et al.
Publicado: (2018)

Resveratrol prevents inflammation and oxidative stress response in LPS-induced human gingival fibroblasts by targeting the PI3K/AKT and Wnt/β-catenin signaling pathways
por: Li, Lihua, et al.
Publicado: (2021)

Emerging Roles of Microglia in Neuro-vascular Unit: Implications of Microglia-Neurons Interactions
por: Ding, Zhe, et al.
Publicado: (2021)

Protective role of exosomes derived from regulatory T cells against inflammation and apoptosis of BV-2 microglia under oxygen-glucose deprivation/reperfusion challenge
por: Yang, Changqing, et al.
Publicado: (2022)

MT1G inhibits the growth and epithelial-mesenchymal transition of gastric cancer cells by regulating the PI3K/AKT signaling pathway
por: Xu, Guofeng, et al.
Publicado: (2022)

PEG-PEI/siROCK2 inhibits Aβ(42)-induced microglial inflammation via NLRP3/caspase 1 pathway
por: Liu, Yunyun, et al.
Publicado: (2021)

Crucial role of autophagy in propofol-treated neurological diseases: a comprehensive review
por: Yu, Sicong, et al.
Publicado: (2023)

EPO activates PI3K-IKKα-CDK1 signaling pathway to promote the proliferation of Glial Cells under hypoxia environment
por: Hu, Gejile, et al.
Publicado: (2022)

Microglia and Microglia-Like Cells: Similar but Different
por: Cuadros, Miguel A., et al.
Publicado: (2022)

NBTI attenuates neuroinflammation and apoptosis partly by ENT1/NLRP3/Bcl2 pathway after subarachnoid hemorrhage in rats
por: Chen, Xiaowei, et al.
Publicado: (2021)

Vitamin K(2) protects against Aβ42-induced neurotoxicity by activating autophagy and improving mitochondrial function in Drosophila
por: Lin, Xiaohui, et al.
Publicado: (2021)

MicroRNA-124: A Key Player in Microglia-Mediated Inflammation in Neurological Diseases
por: Zhao, Jiuhan, et al.
Publicado: (2021)

Role of receptor-interacting protein 1/receptor-interacting protein 3 in inflammation and necrosis following chronic constriction injury of the sciatic nerve
por: Pu, Shaofeng, et al.
Publicado: (2018)

Oligonucleotides suppress PKB/Akt and act as superinductors of apoptosis in human keratinocytes
por: Kippenberger, Stefan, et al.
Publicado: (2009)

Selenium protects against LPS-induced MC3T3-E1 cells apoptosis through modulation of microRNA-155 and PI3K/Akt signaling pathways
por: Huang, Yan, et al.
Publicado: (2020)

Brivaracetam exhibits mild pro-inflammatory features in an in vitro astrocyte-microglia co-culture model of inflammation
por: Ismail, Fatme Seval, et al.
Publicado: (2022)

TREM2 Regulates Heat Acclimation-Induced Microglial M2 Polarization Involving the PI3K-Akt Pathway Following EMF Exposure
por: He, Gen-Lin, et al.
Publicado: (2020)

Editorial: Cell biology of microglia
por: Sepúlveda, M. Rosario, et al.
Publicado: (2023)

Inhibition of miR-25 aggravates diabetic peripheral neuropathy
por: Zhang, Yanzhuo, et al.
Publicado: (2018)

Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke
por: Wang, Man-Man, et al.
Publicado: (2020)

What microglia depletion approaches tell us about the role of microglia on synaptic function and behavior
por: Basilico, Bernadette, et al.
Publicado: (2022)

Fluoxetine attenuates prepulse inhibition deficit induced by neonatal administration of MK-801 in mice
por: Yang, Luyin, et al.
Publicado: (2020)

Brain-derived neurotrophic factor propeptide inhibits proliferation and induces apoptosis in C6 glioma cells
por: Yang, Bangkun, et al.
Publicado: (2017)

Propofol inhibits neuroinflammation and metabolic reprogramming in microglia in vitro and in vivo
por: Guan, Shuyuan, et al.
Publicado: (2023)

The Role of Microglia in Perioperative Neurocognitive Disorders
por: Fan, Wenguo, et al.
Publicado: (2020)

Attack of the Clones: Microglia in Health and Disease
por: Manjally, Amritha Vinayak, et al.
Publicado: (2022)

Editorial: Dysfunctional microglia in neurological disorders
por: Bhusal, Anup, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_agi7f22r10rd01olqejejp56hl