Design principles of a microtubule polymerase

Stu2/XMAP215 microtubule polymerases use multiple tubulin-binding TOG domains and a lattice-binding basic region to processively promote faster elongation. How the domain composition and organization of these proteins dictate polymerase activity, end localization, and processivity is unknown. We sho...

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Detalles Bibliográficos
Autores principales: Geyer, Elisabeth A, Miller, Matthew P, Brautigam, Chad A, Biggins, Sue, Rice, Luke M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999394/
https://www.ncbi.nlm.nih.gov/pubmed/29897335
http://dx.doi.org/10.7554/eLife.34574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999394/
https://www.ncbi.nlm.nih.gov/pubmed/29897335
http://dx.doi.org/10.7554/eLife.34574

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