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Irreversible temperature gating in trpv1 sheds light on channel activation

Temperature-activated TRP channels or thermoTRPs are among the only proteins that can directly convert temperature changes into changes in channel open probability. In spite of a wealth of functional and structural information, the mechanism of temperature activation remains unknown. We have careful...

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Detalles Bibliográficos
Autores principales: Sánchez-Moreno, Ana, Guevara-Hernández, Eduardo, Contreras-Cervera, Ricardo, Rangel-Yescas, Gisela, Ladrón-de-Guevara, Ernesto, Rosenbaum, Tamara, Islas, León D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999395/
https://www.ncbi.nlm.nih.gov/pubmed/29869983
http://dx.doi.org/10.7554/eLife.36372