Inflammatory-induced spinal dorsal horn neurons hyperexcitability is mediated by P2X4 receptors

INTRODUCTION: Purinergic ionotropic P2X receptors (P2RX) are involved in normal and pathological pain transmission. Among them, P2X4 are expressed in dorsal root ganglion and in the spinal cord. Their activation during nerve injury or chronic peripheral inflammation modifies pain sensitivity that le...

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Detalles Bibliográficos
Autores principales: Aby, Franck, Whitestone, Sara, Landry, Marc, Ulmann, Lauriane, Fossat, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999414/
https://www.ncbi.nlm.nih.gov/pubmed/29922748
http://dx.doi.org/10.1097/PR9.0000000000000660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999414/
https://www.ncbi.nlm.nih.gov/pubmed/29922748
http://dx.doi.org/10.1097/PR9.0000000000000660

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