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Inhibition of NF-κB signaling pathway induces apoptosis and suppresses proliferation and angiogenesis of human fibroblast-like synovial cells in rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) is the most common inflammatory arthritis and is a major cause of disability. The nuclear factor-kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway has been reported to be involved in the pathogenesis of RA with unclear mechanisms. Therefo...

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Detalles Bibliográficos
Autores principales: Xia, Zhong-Bin, Meng, Fan-Ru, Fang, Yu-Xuan, Wu, Xia, Zhang, Chun-Wang, Liu, Ying, Liu, Dan, Li, Guo-Qing, Feng, Fan-Bo, Qiu, Hai-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999456/
https://www.ncbi.nlm.nih.gov/pubmed/29879032
http://dx.doi.org/10.1097/MD.0000000000010920