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Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma

The Hedgehog (Hh) signalling pathway is involved in cell differentiation, growth and tissue polarity. This pathway is also involved in the progression and invasion of various human cancers. Osteosarcoma, a subtype of bone cancer, is commonly seen in children and adolescents. Typically, pulmonary ost...

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Detalles Bibliográficos
Autores principales: Yao, Zhihong, Han, Lei, Chen, Yongbin, He, Fei, Sun, Bin, kamar, Santosh, Zhang, Ya, Yang, Yihao, Wang, Cao, Yang, Zuozhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999604/
https://www.ncbi.nlm.nih.gov/pubmed/29899399
http://dx.doi.org/10.1038/s41419-018-0647-1