Inhibition of ANO1/TMEM16A induces apoptosis in human prostate carcinoma cells by activating TNF-α signaling

Overexpression of the Ca(2+)-activated chloride channel ANO1/TMEM16A is implicated in tumorigenesis, and inhibition of ANO1 overexpression suppresses xenograft tumor growth and invasiveness. However, the underlying molecular mechanism for ANO1 inhibition in suppression of tumorigenesis remains unkno...

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Detalles Bibliográficos
Autores principales: Song, Yan, Gao, Jian, Guan, Lizhao, Chen, Xiaoling, Gao, Jianjun, Wang, KeWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999606/
https://www.ncbi.nlm.nih.gov/pubmed/29899325
http://dx.doi.org/10.1038/s41419-018-0735-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999606/
https://www.ncbi.nlm.nih.gov/pubmed/29899325
http://dx.doi.org/10.1038/s41419-018-0735-2

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