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Inhibition of ANO1/TMEM16A induces apoptosis in human prostate carcinoma cells by activating TNF-α signaling
Overexpression of the Ca(2+)-activated chloride channel ANO1/TMEM16A is implicated in tumorigenesis, and inhibition of ANO1 overexpression suppresses xenograft tumor growth and invasiveness. However, the underlying molecular mechanism for ANO1 inhibition in suppression of tumorigenesis remains unkno...
Autores principales: | Song, Yan, Gao, Jian, Guan, Lizhao, Chen, Xiaoling, Gao, Jianjun, Wang, KeWei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999606/ https://www.ncbi.nlm.nih.gov/pubmed/29899325 http://dx.doi.org/10.1038/s41419-018-0735-2 |
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