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非小细胞肺癌患者hOGG1基因启动子区域突变的研究
BACKGROUND AND OBJECTIVE: 8-hydroxygumine DNA glycosylase 1 (OGG1) is a DNA repair enzyme, which can repair damaged DNA by excising 8-dihydro-8-oxoguanine (8-OH-G). Polymorphisms in human OGG1 gene (hOGG1) may alter glycosylase activity, thereby affects its repair to the damaged DNA, resulting in co...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999654/ https://www.ncbi.nlm.nih.gov/pubmed/21426660 http://dx.doi.org/10.3779/j.issn.1009-3419.2011.03.04 |