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Apoptosis and signalling in acid sphingomyelinase deficient cells
BACKGROUND: Recent evidence suggests that the activation of a non-specific lipid scramblase during apoptosis induces the flipping of sphingomyelin from the cell surface to the cytoplasmic leaftet of the plasma membrane. Inner leaflet sphingomyelin is then cleaved to ceramide by a neutral sphingomyel...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59997/ https://www.ncbi.nlm.nih.gov/pubmed/11722792 http://dx.doi.org/10.1186/1471-2121-2-24 |