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RNA干扰GRP75表达改善人肺腺癌细胞对顺铂耐药性

BACKGROUND AND OBJECTIVE: GRP75, a member of HSPs which is overexpressed in some resistant cancer cells, is a molecular chaperone mainly located in mitochondrial membrane. The aim of this study is to investigate the role of GRP75 on the resistant mechanisms of cancer cells by downregulating GRP75 ex...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999707/
https://www.ncbi.nlm.nih.gov/pubmed/21496427
http://dx.doi.org/10.3779/j.issn.1009-3419.2011.04.01