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RNA干扰GRP75表达改善人肺腺癌细胞对顺铂耐药性
BACKGROUND AND OBJECTIVE: GRP75, a member of HSPs which is overexpressed in some resistant cancer cells, is a molecular chaperone mainly located in mitochondrial membrane. The aim of this study is to investigate the role of GRP75 on the resistant mechanisms of cancer cells by downregulating GRP75 ex...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
Publicado: |
中国肺癌杂志编辑部
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999707/ https://www.ncbi.nlm.nih.gov/pubmed/21496427 http://dx.doi.org/10.3779/j.issn.1009-3419.2011.04.01 |