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RNA干扰GRP75表达改善人肺腺癌细胞对顺铂耐药性
BACKGROUND AND OBJECTIVE: GRP75, a member of HSPs which is overexpressed in some resistant cancer cells, is a molecular chaperone mainly located in mitochondrial membrane. The aim of this study is to investigate the role of GRP75 on the resistant mechanisms of cancer cells by downregulating GRP75 ex...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
中国肺癌杂志编辑部
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999707/ https://www.ncbi.nlm.nih.gov/pubmed/21496427 http://dx.doi.org/10.3779/j.issn.1009-3419.2011.04.01 |