Thymic B Cell-Mediated Attack of Thymic Stroma Precedes Type 1 Diabetes Development

Type 1 diabetes (T1D) results from a coordinated autoimmune attack of insulin producing beta cells in the pancreas by the innate and adaptive immune systems, beta cell death being predominantly T cell-mediated. In addition to T cells, peripheral B cells are important in T1D progression. The thymus o...

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Detalles Bibliográficos
Autores principales: Pinto, Ana Isabel, Smith, Jennifer, Kissack, Miriam R., Hogg, Karen G., Green, E. Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999731/
https://www.ncbi.nlm.nih.gov/pubmed/29930554
http://dx.doi.org/10.3389/fimmu.2018.01281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999731/
https://www.ncbi.nlm.nih.gov/pubmed/29930554
http://dx.doi.org/10.3389/fimmu.2018.01281

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