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Thymic B Cell-Mediated Attack of Thymic Stroma Precedes Type 1 Diabetes Development
Type 1 diabetes (T1D) results from a coordinated autoimmune attack of insulin producing beta cells in the pancreas by the innate and adaptive immune systems, beta cell death being predominantly T cell-mediated. In addition to T cells, peripheral B cells are important in T1D progression. The thymus o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999731/ https://www.ncbi.nlm.nih.gov/pubmed/29930554 http://dx.doi.org/10.3389/fimmu.2018.01281 |