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Heparin Oligosaccharides Have Antiarrhythmic Effect by Accelerating the Sodium-Calcium Exchanger
Background: Blockage of the Na(+)/Ca(2+) exchanger (NCX) is used to determine the role of NCX in arrhythmogenesis. Trisulfated heparin disaccharide (TD) and Low Molecular Weight Heparins (LMWHs) can directly interact with the NCX and accelerate its activity. Objective: In this work, we investigated...
Autores principales: | de Godoy, Carlos M. G., Vasques, Ênio R., Caricati-Neto, Afonso, Tavares, José G. P., Alves, Beatriz J., Duarte, Juliana, Miranda-Ferreira, Regiane, Lima, Marcelo A., Nader, Helena B., Tersariol, Ivarne L. dos Santos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999778/ https://www.ncbi.nlm.nih.gov/pubmed/29930947 http://dx.doi.org/10.3389/fcvm.2018.00067 |
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