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慢病毒介导的稳定沉默nm23-H1基因的肺癌细胞株的建立及生物学行为改变

BACKGROUND AND OBJECTIVE: The nm23-H1 gene is an important tumor metastatic suppressor gene. Our previous study showed that the downregulation of nm23-H1 gene expression using small interfering RNA (siRNA) in NL9980 lung cancer cells greatly enhanced their invasiveness. To further explore the molecu...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999872/
https://www.ncbi.nlm.nih.gov/pubmed/22429576
http://dx.doi.org/10.3779/j.issn.1009-3419.2012.03.02