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利用CRISPR/Cas9慢病毒系统构建肺部EZH2基因敲除小鼠

BACKGROUND AND OBJECTIVE: It has been proven that CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated 9) system was the modern gene-editing technology through the constitutive expression of nucleases Cas9 in the mammalian, which binds to the specific site in the...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999930/
https://www.ncbi.nlm.nih.gov/pubmed/29764585
http://dx.doi.org/10.3779/j.issn.1009-3419.2018.05.02