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高分辨熔解曲线法检测非小细胞肺癌p53基因的突变

BACKGROUND AND OBJECTIVE: It has been proven that p53 gene was related to many human cancers. The mutations in p53 gene play an important role in carcinogensis and mostly happened in exon 5-8. The aim of this study is to establish a high resolution melting (HRM) assay to detect p53 mutations from pa...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999946/
https://www.ncbi.nlm.nih.gov/pubmed/22008105
http://dx.doi.org/10.3779/j.issn.1009-3419.2011.10.01