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EGF通过STAT5调控肺腺癌A549细胞中COX-2的机制

BACKGROUND AND OBJECTIVE: It has been proved that cyclooxygenase-2 (COX-2) is a key factor in lung cancer oncogenesis.COX-2 can be induced by a number of cytokines and growth factors and can be regulated by the JAK/STAT signaling pathway.Inhibiting the expression of COX-2 can prevent the development...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000591/
https://www.ncbi.nlm.nih.gov/pubmed/23601296
http://dx.doi.org/10.3779/j.issn.1009-3419.2013.04.01