LRRK 2 gene mutations in the pathophysiology of the ROCO domain and therapeutic targets for Parkinson’s disease: a review

Parkinson’s disease (PD) is the most common movement disorder and manifests as resting tremor, rigidity, bradykinesia, and postural instability. Pathologically, PD is characterized by selective loss of dopaminergic neurons in the substantia nigra and the formation of intracellular inclusions contain...

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Detalles Bibliográficos
Autores principales: Chen, Meng-Ling, Wu, Ruey-Meei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000924/
https://www.ncbi.nlm.nih.gov/pubmed/29903014
http://dx.doi.org/10.1186/s12929-018-0454-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000924/
https://www.ncbi.nlm.nih.gov/pubmed/29903014
http://dx.doi.org/10.1186/s12929-018-0454-0

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