Cargando…

Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

BACKGROUND: Obesity and type II diabetes are linked to increased breast cancer risk in postmenopausal women. Patients treated with the antidiabetic drug metformin for diabetes or metabolic syndrome have reduced breast cancer risk, a greater pathologic complete response to neoadjuvant therapy, and im...

Descripción completa

Detalles Bibliográficos
Autores principales: Giles, Erin D., Jindal, Sonali, Wellberg, Elizabeth A., Schedin, Troy, Anderson, Steven M., Thor, Ann D., Edwards, Dean P., MacLean, Paul S., Schedin, Pepper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000949/
https://www.ncbi.nlm.nih.gov/pubmed/29898754
http://dx.doi.org/10.1186/s13058-018-0974-2