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Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer
BACKGROUND: Obesity and type II diabetes are linked to increased breast cancer risk in postmenopausal women. Patients treated with the antidiabetic drug metformin for diabetes or metabolic syndrome have reduced breast cancer risk, a greater pathologic complete response to neoadjuvant therapy, and im...
Autores principales: | Giles, Erin D., Jindal, Sonali, Wellberg, Elizabeth A., Schedin, Troy, Anderson, Steven M., Thor, Ann D., Edwards, Dean P., MacLean, Paul S., Schedin, Pepper |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000949/ https://www.ncbi.nlm.nih.gov/pubmed/29898754 http://dx.doi.org/10.1186/s13058-018-0974-2 |
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