miR126-5p Downregulation Facilitates Axon Degeneration and NMJ Disruption via a Non–Cell-Autonomous Mechanism in ALS

Axon degeneration and disruption of neuromuscular junctions (NMJs) are key events in amyotrophic lateral sclerosis (ALS) pathology. Although the disease's etiology is not fully understood, it is thought to involve a non–cell-autonomous mechanism and alterations in RNA metabolism. Here, we ident...

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Detalles Bibliográficos
Autores principales: Maimon, Roy, Ionescu, Ariel, Bonnie, Avichai, Sweetat, Sahar, Wald-Altman, Shane, Inbar, Shani, Gradus, Tal, Trotti, Davide, Weil, Miguel, Behar, Oded, Perlson, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001038/
https://www.ncbi.nlm.nih.gov/pubmed/29773756
http://dx.doi.org/10.1523/JNEUROSCI.3037-17.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001038/
https://www.ncbi.nlm.nih.gov/pubmed/29773756
http://dx.doi.org/10.1523/JNEUROSCI.3037-17.2018

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