CCR2 Signal Facilitates Thymic Egress by Priming Thymocyte Responses to Sphingosine-1-Phosphate

The signal mediated by sphingosine-1-phosphate receptor 1 (S1P1) is essential but seemingly insufficient for thymic export of newly generated T cells. Here, we reported the identification of CCR2 as an additional regulator of this process. CCR2 showed a markedly increased expression in the most matu...

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Detalles Bibliográficos
Autores principales: Aili, Abudureyimujiang, Zhang, Jie, Wu, Jia, Wu, Haoming, Sun, Xiuyuan, He, Qihua, Jin, Rong, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001116/
https://www.ncbi.nlm.nih.gov/pubmed/29930553
http://dx.doi.org/10.3389/fimmu.2018.01263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001116/
https://www.ncbi.nlm.nih.gov/pubmed/29930553
http://dx.doi.org/10.3389/fimmu.2018.01263

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