Kinomic profiling of glioblastoma cells reveals PLCG1 as a target in restricted glucose

BACKGROUND: For glioblastoma (GBM) treatments to be effective in vivo, understanding the effects of the tumor microenvironment is imperative. In traditional cell culture conditions, glucose concentrations do not model physiologic levels, nor the diminished concentrations found in tumor niches. We th...

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Detalles Bibliográficos
Autores principales: Walker, Kiera, Boyd, Nathaniel H., Anderson, Joshua C., Willey, Christopher D., Hjelmeland, Anita B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001119/
https://www.ncbi.nlm.nih.gov/pubmed/29946469
http://dx.doi.org/10.1186/s40364-018-0136-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001119/
https://www.ncbi.nlm.nih.gov/pubmed/29946469
http://dx.doi.org/10.1186/s40364-018-0136-9

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