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Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties

BACKGROUND: The initiation and progression of hepatocellular carcinoma (HCC) are largely dependent on its local microenvironment. Adipocytes are an important component of hepatic microenvironment in nonalcoholic fatty liver disease (NAFLD), which is a significant risk factor for HCC. Given the globa...

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Detalles Bibliográficos
Autores principales: Wang, Shihua, Xu, Meiqian, Li, Xiaoxia, Su, Xiaodong, Xiao, Xian, Keating, Armand, Zhao, Robert Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001126/
https://www.ncbi.nlm.nih.gov/pubmed/29898759
http://dx.doi.org/10.1186/s13045-018-0625-1