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Effect of pirfenidone on wound healing in lung transplant patients

BACKGROUND: The drug pirfenidone has been shown to slow the progression and decrease mortality of idiopathic pulmonary fibrosis (IPF). Its exact mechanism is unknown, but it likely inhibits pro-fibrotic cytokine transforming growth factor beta, a known contributor to wound healing. We evaluated whet...

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Detalles Bibliográficos
Autores principales: Mortensen, Amber, Cherrier, Lauren, Walia, Rajat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001132/
https://www.ncbi.nlm.nih.gov/pubmed/29946463
http://dx.doi.org/10.1186/s40248-018-0129-4