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Thoracic and cutaneous sarcoid-like reaction associated with anti-PD-1 therapy: longitudinal monitoring of PD-1 and PD-L1 expression after stopping treatment

BACKGROUND: Immune checkpoint inhibitors (ICI) target T cell inhibitory pathways that are responsible for cancer tolerance by down-modulating immune functions. ICI have revolutionized patients care with lung cancer. Nevertheless, restoring endogenous antitumor T-cell responses can induce immune rela...

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Detalles Bibliográficos
Autores principales: Paolini, Léa, Poli, Caroline, Blanchard, Simon, Urban, Thierry, Croué, Anne, Rousselet, Marie-Christine, Le Roux, Sarah, Labarrière, Nathalie, Jeannin, Pascale, Hureaux, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001149/
https://www.ncbi.nlm.nih.gov/pubmed/29898781
http://dx.doi.org/10.1186/s40425-018-0372-4