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Interferon-γ and Smac mimetics synergize to induce apoptosis of lung cancer cells in a TNFα-independent manner

BACKGROUND: The prognosis of lung cancer is very poor and hence new therapeutic strategies are urgently desired. In this study, we searched for efficacious Smac mimetic-based combination therapies with biomarkers to predict responses for non-small cell lung cancer (NSCLC). METHODS: NSCLC cell lines...

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Detalles Bibliográficos
Autores principales: Hao, Qin, Tang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001173/
https://www.ncbi.nlm.nih.gov/pubmed/29946223
http://dx.doi.org/10.1186/s12935-018-0579-y