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E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes

OBJECTIVE: Aberrant hepatic glucose production contributes to the development of hyperglycemia and is a hallmark of type 2 diabetes. In a recent study, we showed that the transcription factor E2F1, a component of the cell cycle machinery, contributes to hepatic steatosis through the transcriptional...

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Detalles Bibliográficos
Autores principales: Giralt, Albert, Denechaud, Pierre-Damien, Lopez-Mejia, Isabel C., Delacuisine, Brigitte, Blanchet, Emilie, Bonner, Caroline, Pattou, Francois, Annicotte, Jean-Sébastien, Fajas, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001358/
https://www.ncbi.nlm.nih.gov/pubmed/29526568
http://dx.doi.org/10.1016/j.molmet.2018.02.011