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E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes
OBJECTIVE: Aberrant hepatic glucose production contributes to the development of hyperglycemia and is a hallmark of type 2 diabetes. In a recent study, we showed that the transcription factor E2F1, a component of the cell cycle machinery, contributes to hepatic steatosis through the transcriptional...
Autores principales: | Giralt, Albert, Denechaud, Pierre-Damien, Lopez-Mejia, Isabel C., Delacuisine, Brigitte, Blanchet, Emilie, Bonner, Caroline, Pattou, Francois, Annicotte, Jean-Sébastien, Fajas, Lluis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001358/ https://www.ncbi.nlm.nih.gov/pubmed/29526568 http://dx.doi.org/10.1016/j.molmet.2018.02.011 |
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