Directed nickel-catalyzed 1,2-dialkylation of alkenyl carbonyl compounds

A nickel-catalyzed conjunctive cross-coupling of non-conjugated alkenes, alkyl halides, and alkylzinc reagents is reported. Regioselectivity is controlled by chelation of a removable bidentate 8-aminoquinoline directing group. Under optimized conditions, a wide range of 1,2-dialkylated products can...

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Detalles Bibliográficos
Autores principales: Derosa, Joseph, van der Puyl, Vincent A., Tran, Van T., Liu, Mingyu, Engle, Keary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001383/
https://www.ncbi.nlm.nih.gov/pubmed/29997883
http://dx.doi.org/10.1039/c8sc01735b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001383/
https://www.ncbi.nlm.nih.gov/pubmed/29997883
http://dx.doi.org/10.1039/c8sc01735b

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