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Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice
OBJECTIVE: Both Type I and Type II diabetes mellitus result from insufficient functional β-cell mass. Efforts to increase β-cell proliferation as a means to restore β-cell mass have been met with limited success. Suppression of Tumorigenicity 5 (ST5) activates Ras/Erk signaling in the presence of Ep...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001393/ https://www.ncbi.nlm.nih.gov/pubmed/29650351 http://dx.doi.org/10.1016/j.molmet.2018.03.009 |