Cargando…
Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice
OBJECTIVE: Both Type I and Type II diabetes mellitus result from insufficient functional β-cell mass. Efforts to increase β-cell proliferation as a means to restore β-cell mass have been met with limited success. Suppression of Tumorigenicity 5 (ST5) activates Ras/Erk signaling in the presence of Ep...
Autores principales: | Ou, Kristy, Zhang, Jia, Jiao, Yang, Wang, Zhao V., Scherer, Phillipp, Kaestner, Klaus H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001393/ https://www.ncbi.nlm.nih.gov/pubmed/29650351 http://dx.doi.org/10.1016/j.molmet.2018.03.009 |
Ejemplares similares
-
Overexpression of Gjb4 impairs cell proliferation and insulin secretion in primary islet cells
por: Gässler, Anneke, et al.
Publicado: (2020) -
Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice
por: Chartoumpekis, Dionysios V., et al.
Publicado: (2015) -
Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice
por: Jall, Sigrid, et al.
Publicado: (2019) -
Who Has Seen Patients With ST‐Segment–Elevation Myocardial Infarction? First Results From Italian Real‐World Coronavirus Disease 2019
por: Cammalleri, Valeria, et al.
Publicado: (2020) -
Carnitine transporter OCTN2 and carnitine uptake in bovine kidney cells is regulated by peroxisome proliferator-activated receptor β/δ
por: Zhou, Xiaodan, et al.
Publicado: (2014)