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Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolites

OBJECTIVES: 5-HT storing enterochromaffin (EC) cells are believed to respond to nutrient and gut microbial components, and 5-HT receptor-expressing afferent vagal neurons have been described to be the major sensors of nutrients in the GI-tract. However, the molecular mechanism through which EC cells...

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Detalles Bibliográficos
Autores principales: Lund, Mari L., Egerod, Kristoffer L., Engelstoft, Maja S., Dmytriyeva, Oksana, Theodorsson, Elvar, Patel, Bhavik A., Schwartz, Thue W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001397/
https://www.ncbi.nlm.nih.gov/pubmed/29576437
http://dx.doi.org/10.1016/j.molmet.2018.03.004