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A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes

OBJECTIVE: Obesity and type 2 diabetes (T2D) arise from the interplay between genetic, epigenetic, and environmental factors. The aim of this study was to combine bioinformatics and functional studies to identify miRNAs that contribute to obesity and T2D. METHODS: A computational framework (miR-QTL-...

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Detalles Bibliográficos
Autores principales: Gottmann, Pascal, Ouni, Meriem, Saussenthaler, Sophie, Roos, Julian, Stirm, Laura, Jähnert, Markus, Kamitz, Anne, Hallahan, Nicole, Jonas, Wenke, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald, Blüher, Matthias, Fischer-Posovszky, Pamela, Vogel, Heike, Schürmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001404/
https://www.ncbi.nlm.nih.gov/pubmed/29605715
http://dx.doi.org/10.1016/j.molmet.2018.03.005