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A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes
OBJECTIVE: Obesity and type 2 diabetes (T2D) arise from the interplay between genetic, epigenetic, and environmental factors. The aim of this study was to combine bioinformatics and functional studies to identify miRNAs that contribute to obesity and T2D. METHODS: A computational framework (miR-QTL-...
Autores principales: | Gottmann, Pascal, Ouni, Meriem, Saussenthaler, Sophie, Roos, Julian, Stirm, Laura, Jähnert, Markus, Kamitz, Anne, Hallahan, Nicole, Jonas, Wenke, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald, Blüher, Matthias, Fischer-Posovszky, Pamela, Vogel, Heike, Schürmann, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001404/ https://www.ncbi.nlm.nih.gov/pubmed/29605715 http://dx.doi.org/10.1016/j.molmet.2018.03.005 |
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