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ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells

Inducible costimulator (ICOS) plays an important role in the suppressive immunity mediated by regulatory T cells (Tregs), but the molecular regulation mechanism is not well known. Here we performed a study to explore the possible mechanism by which ICOS regulates the suppressive functions and surviv...

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Detalles Bibliográficos
Autores principales: Chen, Qianmei, Mo, Lijun, Cai, Xiangsheng, Wei, Lili, Xie, Zhengneng, Li, Hongwei, Li, Jinlong, Hu, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001412/
https://www.ncbi.nlm.nih.gov/pubmed/29910670
http://dx.doi.org/10.7150/ijms.23940