Cargando…

ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells

Inducible costimulator (ICOS) plays an important role in the suppressive immunity mediated by regulatory T cells (Tregs), but the molecular regulation mechanism is not well known. Here we performed a study to explore the possible mechanism by which ICOS regulates the suppressive functions and surviv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Qianmei, Mo, Lijun, Cai, Xiangsheng, Wei, Lili, Xie, Zhengneng, Li, Hongwei, Li, Jinlong, Hu, Zhiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001412/ https://www.ncbi.nlm.nih.gov/pubmed/29910670 http://dx.doi.org/10.7150/ijms.23940

Ejemplares similares

Regulatory T cells, especially ICOS(+) FOXP3(+) regulatory T cells, are increased in the hepatocellular carcinoma microenvironment and predict reduced survival
por: Tu, Jian-Fei, et al.
Publicado: (2016)

CD4(+)ICOS(+)Foxp3(+): a sub-population of regulatory T cells contribute to malaria pathogenesis
por: Chauhan, Rubika, et al.
Publicado: (2022)

ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection
por: Redpath, Stephen A, et al.
Publicado: (2013)

CD4(+)T Cell Subset Profiling in Biliary Atresia Reveals ICOS(−) Regulatory T Cells as a Favorable Prognostic Factor
por: Zhang, Shuhao, et al.
Publicado: (2019)

ICOS costimulation is indispensable for the differentiation of T follicular regulatory cells
por: Panneton, Vincent, et al.
Publicado: (2023)

Norcantharidin enhances antitumor immunity of GM‐CSF prostate cancer cells vaccine by inducing apoptosis of regulatory T cells
por: Mo, Lijun, et al.
Publicado: (2018)

Shikonin suppresses the epithelial-to-mesenchymal transition by downregulating NHE1 in bladder cancer cells
por: Mo, Lijun, et al.
Publicado: (2021)

ICO investors
por: Fahlenbrach, Rüdiger, et al.
Publicado: (2020)

Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity
por: Jia, Min, et al.
Publicado: (2020)

Mesothelin Virus-Like Particle Immunization Controls Pancreatic Cancer Growth through CD8(+) T Cell Induction and Reduction in the Frequency of CD4(+)foxp3(+)ICOS(−) Regulatory T Cells
por: Zhang, Sheng, et al.
Publicado: (2013)

Expression of CD4+CD25+CD127(Low) regulatory T cells and cytokines in peripheral blood of patients with primary liver carcinoma
por: Zhou, Wenchao, et al.
Publicado: (2020)

Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity
por: Zong, Xinying, et al.
Publicado: (2021)

Foxp1 is critical for the maintenance of regulatory T-cell homeostasis and suppressive function
por: Ren, Jiazi, et al.
Publicado: (2019)

MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux
por: Mo, Lijun, et al.
Publicado: (2022)

Colloque ICO '89
por: Moulin, B, et al.
Publicado: (1989)

Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3(int)CD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies
por: Pouw, Juliëtte N., et al.
Publicado: (2022)

The rationale behind targeting the ICOS-ICOS ligand costimulatory pathway in cancer immunotherapy
por: Solinas, Cinzia, et al.
Publicado: (2020)

Role of endocytosis and trans‐endocytosis in ICOS costimulator‐induced downmodulation of the ICOS Ligand
por: Aragoneses‐Fenoll, Laura, et al.
Publicado: (2021)

Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3(+) inducible regulatory T cells
por: Klunker, Sven, et al.
Publicado: (2009)

ICOS signaling limits regulatory T cell accumulation and function in visceral adipose tissue
por: Mittelsteadt, Kristen L., et al.
Publicado: (2021)

FOXP4‐AS1 is a favorable prognostic-related enhancer RNA in ovarian cancer
por: Hua, Tian, et al.
Publicado: (2021)

UXT is a novel regulatory factor of regulatory T cells associated with Foxp3
por: Li, Weina, et al.
Publicado: (2014)

Norcantharidin Induces Immunogenic Cell Death of Bladder Cancer Cells through Promoting Autophagy in Acidic Culture
por: Xu, Lili, et al.
Publicado: (2022)

Author Correction: Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3(int)CD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies
por: Pouw, Juliëtte N., et al.
Publicado: (2023)

ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain
por: O’Brien, Carleigh A., et al.
Publicado: (2020)

Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells
por: Han, Yixiang, et al.
Publicado: (2018)

DNA facilitates heterodimerization between human transcription factors FoxP1 and FoxP2 by increasing their conformational flexibility
por: Coñuecar, Ricardo, et al.
Publicado: (2023)

Sustained suppression by Foxp3(+) regulatory T cells is vital for infectious transplantation tolerance
por: Kendal, Adrian R., et al.
Publicado: (2011)

CD4(+)CD25(+)Foxp3(+) regulatory T cells suppress NKG2D-mediated NK cell cytotoxicity in peripheral blood
por: Geng, Xu, et al.
Publicado: (2019)

Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies
por: Rujas, Edurne, et al.
Publicado: (2020)

The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis
por: Yang, Chen, et al.
Publicado: (2017)

Co-expression of Foxp3 and Helios facilitates the identification of human T regulatory cells in health and disease
por: Morina, Lyra, et al.
Publicado: (2023)

Comprehensive analysis of the role of ICOS ( CD278 ) in pan-cancer prognosis and immunotherapy
por: Zhao, Xiashuang, et al.
Publicado: (2023)

T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer
por: Ni, Huanhe, et al.
Publicado: (2022)

Regulation of T follicular helper cells by ICOS
por: Hutloff, Andreas
Publicado: (2015)

ICOS regulates ILC2s in asthma
por: Maazi, Hadi, et al.
Publicado: (2015)

ICOS Co-Stimulation: Friend or Foe?
por: Wikenheiser, Daniel J., et al.
Publicado: (2016)

ICOS Coreceptor Signaling Inactivates the Transcription Factor FOXO1 to Promote Tfh Cell Differentiation
por: Stone, Erica L., et al.
Publicado: (2015)

Neutralization of IL-4 and IFN-γ Facilitates inducing TGF-β-induced CD4(+)Foxp3(+) Regulatory Cells
por: Tao, Xiaojuan, et al.
Publicado: (2008)

Signaling Through gp130 Compromises Suppressive Function in Human FOXP3(+) Regulatory T Cells
por: Bin Dhuban, Khalid, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nh1e1sngeo7jn43bj26aaag1a3