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Chronic Alcohol Consumption Inhibits Autophagy and Promotes Apoptosis in the Liver

Background: Chronic alcohol consumption is a major cause of liver injury. However, the molecular mechanisms by which alcohol impairs hepatocellular function and induces cell death remain unclear. Macroautophagy (hereafter called 'autophagy') is a degradation pathway involved in the surviva...

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Detalles Bibliográficos
Autores principales: Menk, Mario, Graw, Jan Adriaan, Poyraz, Deniz, Möbius, Nadine, Spies, Claudia D., von Haefen, Clarissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001414/
https://www.ncbi.nlm.nih.gov/pubmed/29910672
http://dx.doi.org/10.7150/ijms.25393