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Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors

Mucinous type of epithelial ovarian cancer (MuOC) is a unique subtype with a poor survival outcome in recurrent and advanced stages. The role of type‐specific epigenomics and its clinical significance remains uncertain. We analyzed the methylomic profiles of 6 benign mucinous adenomas, 24 MuOCs, 103...

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Detalles Bibliográficos
Autores principales: Liew, Phui‐Ly, Huang, Rui‐Lan, Weng, Yu‐Chun, Fang, Chia‐Lang, Hui‐Ming Huang, Tim, Lai, Hung‐Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001480/
https://www.ncbi.nlm.nih.gov/pubmed/29451304
http://dx.doi.org/10.1002/ijc.31324