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miR‐34b‐5p inhibition attenuates lung inflammation and apoptosis in an LPS‐induced acute lung injury mouse model by targeting progranulin

Inflammation and apoptosis play important roles in the initiation and progression of acute lung injury (ALI). Our previous study has shown that progranulin (PGRN) exerts lung protective effects during LPS‐induced ALI. Here, we have investigated the potential roles of PGRN‐targeting microRNAs (miRNAs...

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Detalles Bibliográficos
Autores principales: Xie, Wang, Lu, Qingchun, Wang, Kailing, Lu, Jingjing, Gu, Xia, Zhu, Dongyi, Liu, Fanglei, Guo, Zhongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001482/
https://www.ncbi.nlm.nih.gov/pubmed/29150939
http://dx.doi.org/10.1002/jcp.26274