POLARIS: Polygenic LD‐adjusted risk score approach for set‐based analysis of GWAS data

Polygenic risk scores (PRSs) are a method to summarize the additive trait variance captured by a set of SNPs, and can increase the power of set‐based analyses by leveraging public genome‐wide association study (GWAS) datasets. PRS aims to assess the genetic liability to some phenotype on the basis o...

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Detalles Bibliográficos
Autores principales: Baker, Emily, Schmidt, Karl Michael, Sims, Rebecca, O'Donovan, Michael C., Williams, Julie, Holmans, Peter, Escott‐Price, Valentina, Consortium, with the GERAD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001515/
https://www.ncbi.nlm.nih.gov/pubmed/29532500
http://dx.doi.org/10.1002/gepi.22117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001515/
https://www.ncbi.nlm.nih.gov/pubmed/29532500
http://dx.doi.org/10.1002/gepi.22117

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