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Hyperpolarized ketone body metabolism in the rat heart

The aim of this work was to investigate the use of (13)C‐labelled acetoacetate and β‐hydroxybutyrate as novel hyperpolarized substrates in the study of cardiac metabolism. [1‐(13)C]Acetoacetate was synthesized by catalysed hydrolysis, and both it and [1‐(13)C]β‐hydroxybutyrate were hyperpolarized by...

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Detalles Bibliográficos
Autores principales: Miller, Jack J., Ball, Daniel R., Lau, Angus Z., Tyler, Damian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001529/
https://www.ncbi.nlm.nih.gov/pubmed/29637642
http://dx.doi.org/10.1002/nbm.3912