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MicroRNA‐130b targets PTEN to induce resistance to cisplatin in lung cancer cells by activating Wnt/β‐catenin pathway

More and more studies indicate the relevance of miRNAs in inducing certain drug resistance. Our study aimed to investigate whether microRNA‐130b‐3p (miR‐130b) mediates the chemoresistance as well as proliferation of lung cancer (LC) cells. MTS assay and apoptosis analysis were conducted to determine...

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Detalles Bibliográficos
Autores principales: Zhang, Qiang, Zhang, Bin, Sun, Leina, Yan, Qingna, Zhang, Yu, Zhang, Zhenfa, Su, Yanjun, Wang, Changli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001533/
https://www.ncbi.nlm.nih.gov/pubmed/29653464
http://dx.doi.org/10.1002/cbf.3331