FBW7 suppresses metastasis of colorectal cancer by inhibiting HIF1α/CEACAM5 functional axis

F-box and WD repeat domain-containing 7 (FBW7) functions as a major tumor suppressor by targeting oncoproteins for degradations. FBW7 has been reported to be one of the most frequently mutated genes in colorectal cancer (CRC). However, its roles and possible mechanisms in the development of CRC are...

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Detalles Bibliográficos
Autores principales: Li, Qingguo, Li, Yaqi, Li, Jing, Ma, Yanlei, Dai, Weixing, Mo, Shaobo, Xu, Ye, Li, Xinxiang, Cai, Sanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001674/
https://www.ncbi.nlm.nih.gov/pubmed/29910683
http://dx.doi.org/10.7150/ijbs.24505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001674/
https://www.ncbi.nlm.nih.gov/pubmed/29910683
http://dx.doi.org/10.7150/ijbs.24505

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